Martín-Grau M, Kamstra JH, Hyötyläinen T, Orešič M, Song Y, Veličković N, Djordjevic A, Milutinović DV, Jackson RF, van Vorstenbosch R, Massart J. The Hepato-Exposome Axis: How Endocrine Disruptors Hijack Liver Receptors to Drive MASLD. Journal of Hepatology. 2026 Jun 22. doi: 10.1016/j.jhep.2026.06.021. PMID: 42331229.
Song Y, Kumar V, Tanabe S, Villeneuve DL, Wittwehr C. Accelerating AOP Development in the AOP-Wiki with AI: A Practical Road Map for the Community. Environmental Science & Technology. 2026;60(21):14777–14781. doi.org/10.1021/acs.est.6c05148. PMID: 42151093.
Barbosa JMG, Alijagic A, Nguyen AH, Castro-Alves V, Valgueblasse L, Orešič M, Hyötyläinen T. PFAS exposure modulates mitochondrial susceptibility in steatotic hepatocytes. Environment International. 2026;213:110337.doi.org/10.1016/j.envint.2026.110337. PMID: 42217317.
Alijagic A, Orešič M, Hyötyläinen T. Perfluorohexyloctane: More than Meets the Eye? Chem Res Toxicol. 2026 Feb 16;39(2):205-207. doi: 10.1021/acs.chemrestox.5c00507. Epub 2026 Feb 2. PMID: 41628141; PMCID: PMC12914703.
Alijagic A, Chaker J, Barbosa JMG, Duberg D, Castro-Alves V, Dickens AM, Orešič M, Hyötyläinen T. Metabolic effects and biotransformation of perfluorohexyloctane in human hepatocytes. Environ Int. 2026 Feb;208:110112. doi: 10.1016/j.envint.2026.110112. Epub 2026 Jan 29. PMID: 41628539.
Song Y, Fan X, Hultman MT, Christou M, Rundberget JT, Klefbom CK, Lin Y, Sun Y, Huang J, Xie L. Next Generation Risk Assessment of Emerging PFOA Alternatives Using Integrated New Approach Methodologies. Environmental Science & Technology. 2025 Nov 21; doi.org/10.1021/acs.est.5c11122. Epub ahead of print.
Nguyen AH, Castro-Alves V, Holmström Flores E, Barbosa JMG, Kråkström M, Reinivuori P, Kauko O, Dickens A, Orešič M, Hyötyläinen T. The SIMPLIFY Protocol: A Monophasic Extraction System Suitable for Exposomics, Metabolomics, Lipidomics, and Proteomics Research. Anal Chem. 2025 Dec 2;97(47):26175-26183. doi: 10.1021/acs.analchem.5c05322. Epub 2025 Nov 19. PMID: 41258906; PMCID: PMC12676512.
Dileo E, Saba F, Parasiliti-Caprino M, Rosso C, Bugianesi E. Impact of Sexual Dimorphism on Therapy Response in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease: From Conventional and Nutritional Approaches to Emerging Therapies. Nutrients. 2025;17(3):477. doi:10.3390/nu17030477.
Alijagic A, Sinisalu L, Duberg D, Kotlyar O, Scherbak N, Engwall M, Orešič M, Hyötyläinen T. Metabolic and phenotypic changes induced by PFAS exposure in two human hepatocyte cell models. Environment International. 2024 Aug 17; 190190:108820. doi.org/10.1016/j.envint.2024.108820. Epub ahead of print. PMID: 38906088.
